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If you need help please visit www.hopeline.com or call 1-800-442-HOPE.

Demystifying Depression is a great article which helped me understand some of the ways depression was affecting me.

The Harmful Impacts of Confusing Pleasure With Happiness

The Addictive Properties of Sugar

And the impact of diet on all other aspects of our lives.

Important Lessons From Brain Scans

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Zoloft is a drug that was released by the Pfizer corporation in 1991 which aimed at fighting depression. The FDA approved Zoloft in October of 1997. Zoloft is a member of the Selective Serotonin Reuptake Inhibitor family, which increases serotonin levels in the synapse by blocking serotonin reuptake into brain cells. Official Zoloft Site
If you or someone you know has had a problem with Zoloft feel free to call the advertising section of FDA at (301) 827-2828. Also fill out the Medwatch form and also call FDA at 1-800-FDA 1088 press 0 or call (301) 443-1240.
Zoloft Feedback and Side Effects

I have been taking Zoloft for 6 mths for anxiety. I am pleased with the results and will continue to use it. Side effects I have experienced include night sweats and bad dreams, aside from this I feel fantastic.

Posted by: from prior site at November 27, 2003 12:27 PM


Posted by: from prior site at November 27, 2003 12:28 PM

My husband has been taking Zoloft for several months now. I was amazed at the difference it made in his personality just a short time after he began the medication. He went from an angry, grumpy person to normal. It has been great. However, he also has begun to question his own values and spiritual beliefs and has begun to act in ways contrary to those beliefs in accord with his newfound "realizations." He has asked his psychiatrist if this could be a side effect of the Zoloft and I, too, have asked my psychiatrist about this. Neither psychiatrist believes this is being caused by the medicaiton. I would be very curious to know anyone's thoughts on this matter and whether this has happened to anyone else as a result of beginning this medication. Needless to say, this turn of events, while improving our home life in many ways, has caused a great upset in others. Any assistance offered would be appreciated.

Posted by: tz at November 27, 2003 1:20 PM

I was taking paxil and now I am on Zoloft, I am loosing weight (not much) it also says that is one of the side effects.

Posted by: SM at November 27, 2003 1:54 PM

I have been seeing what I can find out about Zoloft on the internet when I came across your page. It seems to have only negative feedback. I would like to say that I have been taking Zoloft for over 3 years now and it is the best thing that has ever happened to me. Since as far back as I can remember I was a depressed child and then adult, with violent mood swings and constant thoughts of death being the answer, yet not having the courage to do anything about it, thus living in a horrible suspended state most of the time with little hope. This was not a constant state, but happened regularly enough to make life a misery overall. I have had some side effects, unusual dreams and muscle spasms, but they donít really cause me any real problems and I have gotten used to them. These minor side effects I consider a tiny hinderance compared to the benefits Zoloft has provided in improving my mental state. After reading all the negative feedback, I can only conclude that perhaps Zoloft is more effective for a person with my condition, and is being misdiagnosed in the cases where it is being found unhelpful or even harmful. Of course I hope that being on Zoloft long term does not cause me to develop any longer term side effects which might not yet be known, as I do not intend ever stopping taking it, as I cannot envisage going back to the constant mental battles I suffered before I started taking it. All I can suggest to people who are worried about taking Zoloft when prescribed, is that they keep in close contact with their doctor and relay any problems that they thing it may be causing them. As I live in Australia it would also seem that it is a lot cheaper here as the government must be subsidising it, as I only pay around $22 for a monthís supply. I seem to be benefiting all round!

Posted by: Dianne at February 3, 2004 4:34 PM

I like Zoloft. It makes me feel much better. I do yawn alot though. Sometimes when someone says something real funny I start laughing hesterically and I can't stop. I have to get up and leave the room and go hhide someplace until I get under control. Do you think this sounds nutty? Oh and sometimes I feel more nrevous than normally.

Posted by: kb at February 10, 2004 11:01 PM

I have been on Zoloft for 7 months. I have had depression all of my life. The first two weeks after starting it I was very sleepy and felt disconnected from my body. It did go away. I have had no trouble sleeping, no headaches and no nausea. My depression is much better, but not gone. I have been diagnosed as bi-polar. The side effects I have experienced are diarrea, loss of appetite and weight loss. I have lost 7 pounds due to this and 5 pounds due to a surgery. I went from 50 mg to 100 mg.That was when the weight loss and the appetite loss started (approximately 2 1/2 months into it).

Posted by: Della Slagle at March 18, 2004 3:48 AM

I am a psychology MA. I've taken Zoloft for 5 years now, for Panic Disorder. I started on 50 mg and after two months went up to 100 mg. I still take it. I neither gained nor lost any weight, but I do have an increased appetite, have slight nasal problems, soft stool, palpitations and headaches. When I skip a day or so (usually due to refilling a prescription) I get the brain-zaps and mania. But....considering that before Zoloft I was unable to function or to hardly get out of bed, I'll take the side affects.
Those who are complaining of major problems because they switched drugs quickly or stopped cold-turkey, don't ever, ever do this! These are drugs that mess with your brain chemicals. You have to taper off slowly before switching or quitting. Otherwise you will have serious problems. Also remember that Zoloft does not work for everybody. If it's not working or has stopped working, or is causing side effects much worse than your original illness, either you need a different med or a different doctor (because you aren't really sick....your problem is emotional, not neurochemical).

Posted by: anonymous at May 21, 2004 5:18 PM

I suffer from OCD + high anxiety...Zoloft is a God -send...

I feel much better & don't ever want to go off them.

The only side effect I've had is weight gain..20 kg's..that's a bit too much...but with a calorie controlled diet & over the counter
appetite suppressants I have lost 13.5 kgs & will reach my ideal weight soon.
I love ZOLOFT!

Posted by: John at June 27, 2004 9:09 PM

I've taken zoloft for about two years now. Had depression all my life, had past (not so good) experience with ludiomil (migraines, falling asleep during the day, weight gain) and stopped taking it about 15 years ago.

First few days of Zoloft were interesting, it felt as something was being "adjusted" in my brain. Took me a little while to get acquainted with my new personality, but I like me the way I am now, so does my spouse.

Zoloft does not have the creativity-destroying effect that tricyclics had for me, which is extremely important and is why I couldn't handle taking Ludiomil any longer, that turned me into a robot.

Side effects from Zoloft are minor: bit looser in the bowels (no problem, I like being regular), weird very vivid dreams, dry mouth for the first few days but that is now gone, was always a problem on tricyclics. Sex drive is a little lower than it was, orgasm feels "different" but not in a bad way, that part was pretty numb on tricyclics.

I see no reason to stop taking Zoloft as it's really improved my life and made me a nicer person. I guess I'm a posterchild for the stuff, this is the way it's supposed to work and I'm very happy with it.

Posted by: at July 1, 2004 10:43 PM

I've been taking Zoloft for a long while now. It's only helped me, I've had no side effects on it.

I think what people don't realize about these medicines is that they're very specific to the person taking them. They're not all bad or all good. It depends on the person's body chemistry. So if one doesn't work, you have to try another.

I also wanted to say I love Zoloft's ads with the blobby dudes. They're soooo cute!

Posted by: Jackie at July 24, 2004 9:55 PM

I suffer from panic attacks. I was on Zoloft 50mg two years ago. I quit taking it and within 5 months the panic attacks came back. I am currently taking 25mg of Zoloft (1 month) and the panic attacks are gone. Everyone's body is different, but Zoloft works well for me. Some initial side effects are much better then panic attacks.

Posted by: anonymous at July 31, 2004 1:23 PM

have been taking zoloft for one week waking up hot and slight increase in anxiety not as depressed 50mg a day have been on zoloft before cant remember it taking this long to take effect also waking with rapid pulse should i be more patient

Posted by: at September 6, 2004 9:13 PM

I have been taking zoloft for three weeks, the first week my depression instensified, by the end of the 2nd week I was feeling better, sleeping thru the night. The 3rd week I now feel pratically back to normal. Side effects have been feeling tired in the afternoon and some delayed stuff going on with sex. I plan to take the full dose for another month and then wean off it.

Posted by: Phil at September 9, 2004 9:07 PM

I started taking Zoloft somewhere around 6 months ago. I was started at 50 mg but have since moved up to 75. It causes me to be constantly tired and lethargic, as well as jittery. After about 4 months on Zoloft, it tapered off and stopped working entirely, and since then I've gotten far worse off then I originally was. Now all my original depression symptons are back, plus some.

Posted by: Ashley at October 4, 2004 4:18 AM

I suffered from panic, compulsize thinking, and trouble sleeping for years. A small dose of Zoloft made me feel great right away. Happy and sleeping well. little side effects. after a couple months we needed to increas dosage to get the same level of effect. after a year added Serzone which had a dramatic but different effect, peacefull meditative. higher dosage of Serzone lead to tired, memory and concentration issues. Currently cutting down slowly on the serzone, but would like to keep the Zoloft. Im a 44 year old Male, I take 150mg Zoloft and 450mg Serzone per day.

Posted by: Bill at October 7, 2004 8:11 AM

Since I started zoloft about 6 months ago I have had a positive effect. First, I lost 10 pounds in 5 months. Afterwards, I become more confident and assertive in expressing what I want out of life and what I want from the people around me. Some of them were negative and had to be dismissed, others who were positive are still around. I found that I have been extremely depressed and diagnosed with major depression by my doctor. Well zoloft's effect have been pretty good. I lost weight which I have been struggling with all my life and I'm more confident about myself and my life!

Posted by: Bianca at October 21, 2004 12:27 PM

I just want to comment on this post:

My husband has been taking Zoloft for several months now. I was amazed at the difference it made in his personality just a short time after he began the medication. He went from an angry, grumpy person to normal. It has been great. However, he also has begun to question his own values and spiritual beliefs and has begun to act in ways contrary to those beliefs in accord with his newfound "realizations."

Something about this is hilarious - Talk to your doctor if you feel any of these side-effects:

- Spiritual enlightenment
- Understanding of the meaning of life
- Feelings of God-like connections, wholeness

Posted by: Matt at October 28, 2004 8:17 AM

I started taking zoloft about a month ago and increased the dosage from 50 to 75 to 100mg. I felt immediate improvement but in the last week my depression feels like it has come back and I'm back where I started. Could this be caused by the increase in dosage or is it normal and will work its self out eventually?

Posted by: amanda at April 25, 2006 2:07 PM


Posted by: ANDREA at May 10, 2006 1:28 PM

I just started taking Zoloft today...I feel pretty strange so far. I am hoping that the yawning and the feeling that I am somehow "disconnected" will go away. I had these same feelings with Paxil CR, but I don't think that I took it long enough to allow the side effects to disappear.

Posted by: at May 17, 2006 11:19 PM

I started taking zoloft 5 years ago. I like Zoloft and feel well with it.
20 years ago II have my first depression. I used other drugs and I have lot of side effects.
After this first depressions I feel permanent need of this kind of drugs. If I stop I start to feel tired, sad, no concentration, lack of memory.
I am trying again to get off Zoloft. I am experiencing some head confusion and feeling tired.
There are any problem using Zoloft during years?

Posted by: atinan at July 19, 2006 7:13 PM

I have been taking Zoloft for about two months for severe anxiety. I had no idea how bad my anxiety was until I started taking Zoloft and now feel "normal." The only side effects that I have noticed are that it's much harder for me to wake up and get moving than it used to be (I used to pop out of bed as soon as my eyes opened at 6:00 AM). Once I am moving, however, I seem to be fine. Also, I seem to be much thirstier than before.
Being about to feel as good as I do and not be ruled by panice makes those things seem non-existant to me. I'm very glad to be taking Zoloft.


Posted by: Jenna at July 20, 2006 9:39 PM

I took Zoloft about four years ago for a two-year period, and I just started taking it again two days ago. I have had only a little nausea, but it is NOTHING compared to the three days of hell I experienced while on Lexapro. When I last took it, I dieted, exercised, and lost 50 pounds! I did not have weird dreams or anxiety or loss of libido, and I felt overall much better able to concentrate and cope with life in general. I was also in weekly therapy at the time. If a particular drug or combination of drugs doesn't work for you, talk to your doctor!

I also have to agree about weening off from this drug slowly and under a doctor's care. The side effects of stopping can be scary. I had vertigo for about 3 months, but I tried to keep myself hydrated and healthy in other ways and that helped.

Posted by: Wendi at July 26, 2006 4:01 PM

I started .25 milligrams of Zoloft last night for chronic anxiety. I had morbid thoughts when I woke up. Have felt o.k. today. I am kind of scared of it because of all the horror stories I've heard, but I know it is different for each person.

Posted by: Will at August 1, 2006 4:00 PM

I have been on Zoloft for three wekks now. The first few days were interesting. I felt a little "off". But my usual mood was anger, so I kind of had fun with the doped up feeling. After a few days, my head cleared. I was definetly Aware that something was happening inside my head. Now, on wek three, I feel like a brand new person. My days anre clear, calm and focused. I am amazed at the positve outcome.

Posted by: Frank at August 4, 2006 3:29 PM

I started taking Zoloft 6 years ago after being diagnozed with panic disorder. It took about three months to work completely and I worked up to a dose of 150 mg. After I had not had any anxiety for a few weeks my doctor reduced my dose to a 100, then 50 mg. I tried to wean off but the panic returned so I have been on a 50 mg dose for 5 1/2 years. When I was on 150 mg I did suffer sexual disfunction but at my 50 mg dose I have not side effects at all. Like other, I feel "normal" and regret spending such a long time arranging my life around panic and anxiety. Ideally, I would like to live without medication but really I would rather be dead than to live in the constant state of horror and panic I was in right before going on Zoloft.

Posted by: Kyle at August 6, 2006 2:50 PM

I have depression/anxiety. I started on 25mg of Zoloft for one week and am on day 5 of my 2nd week at 50mg. I'm really out of it, anxious and tired at the same time and getting headaches and generally feel malaise. Does this subside after being on the drug for awhile? I'm using Klonopin to combat what I hope is just initial anxiety.

Posted by: Jess at August 7, 2006 12:59 PM

hi there. i have been on zoloft for about6 months now. i was put on it after having my 2nd son and experianced high anxiety . I dont have much energy and feel tired alot of the time. i am currently taking 50 mg of sertraline do you htink this could be fromt he sertraline or the anxiety itself. my son is now almost 11 months im jsut wondering when i will get my energy back. thanx

Posted by: tiffany at August 7, 2006 10:04 PM

I started taking Zoloft 2 weeks ago for compulsive negative thoughts and a never-ending sadness. Everyday I felt this begging desperation from within; I think my mundane routine could have contributed. I go to the gym religiously and do vigorous cardio because I felt it was a 'natural anti-depressant'- which really helps. However, I struggled with illegal drugs and abusing prescription drugs since age 14. Since quitting drugs, I've maintained a stable life- though using marijuana daily for my 'mood'. That was OK for 6 months, even did GREAT in school. But going to work stoned was not easy, When I wasn't high I experienced angry out-bursts; my crying tantrums and petty fights with loved ones, especially a sweet boyfriend. I actually pulled a knife on myself one night after not getting my way/ not liking his attitude. I realize I probably damaged my nuero-balance (spelling?) and should seek help. I was WARNED not to take Zoloft by friends and the Internet. I have high anxiety and repetitive thoughts- so I also take xanax daily (.25) it takes some discipline not to abuse the xanax- but I'm doing well! I am very concious of side effects, I have experience with withdrawl & prescribtion. However I am optomistic- I am able to clearly realize if a situation that would previously make me angry- is really worth it. I pick my battles and don't carry that "weight". I'm not gona lie, the first 5 days SUCKED. Wanted to share my story cuz I see so much negative feedback. Keep an open mind- know your body, as they say "patient heal thyself" only you know for sure whats good for ya.

thanks friends.

Posted by: Stephy at August 30, 2006 7:54 PM

Oh yeah, and the yawning----
the yawning---
that was interesting.


Posted by: Sarah at August 30, 2006 7:57 PM

I have been taking zoloft 50 mg already for a month and a half. I feel fine but I am worried since it has been difficult for me to sleep well. I wake up two or three times at night. I do not remember what my dreams are about and I am suffering of continuos diarrea and uncontrolled bowel movements. I do not know if it has to be with zoloft but since I am taking it things has been like that. Even more I experienced a lack of sex drive that does not allow me to experience orgarsm. Despite this I am still taking the zoloft because it has helped me a lot to feel relaxed instead of the anxiety I used to have continuously. I have not lose weight. But I do remember that when I took lexapro 10 mg I gained a lot of weight. It is true that lexapro makes you feel without appetite, but my eating habits have changed and it is good for me since I do not have the crave for sweets things anymore. That has been my experience with zoloft. I am still worried about the uncontrolled bowel movements, these are at any time and it is embarrasing. Thanks I hope my experience will help somebody else to understand the different side effects this pill can makes us experience.

Posted by: gloria at September 2, 2006 12:54 PM

Can any one really state three 3 Positive effects of Zoloft(What target symptoms affected?)
because a friend want to take itbut i am scare to allow him to take it.

Posted by: Matthew at September 14, 2006 11:00 PM

I was prescribed Sertraline to aid my recovery from my 7 year battle with bulimia.
I was so reluctant to take any medication for depression, but gave in when i saw my reflection in the doctors examining room.
It was changed my life, a week later he said i looked like a different person. I was back to how i was before and it helped in my recovery.
However i was advised not to stay on it for too long, it has been 3 years now, and i am beginning to wish i had come off it sooner.

I think it should be advised for anyone to stop taking the drug 3 months after the full effects are seen.
It is non addictive (something i was worried about) as i really dont feel the need to take it anymore and i often miss doses and dont even think about it.
Its imporatnat, ive learned, to not think its the drug working and that its you thats changing, this is just a catalyst in recovery. if you get into this way of thinking, the side effects and anxieties of being on the drug will disappear.

but its fair to say that everyone is different and what works for some, may not work for others.

For me, Sertraline/Zoloft has been my saviour.

Posted by: Jenna at October 7, 2006 7:35 PM

I started taking 12.5mg of Zoloft and I never really "woke up" from the drug until 4 or 5pm. I can agree with some on the yawning. I had a constant pressure in my forehead/behind my eyes and it felt like I just wanted to keep my eyes closed all day. Who wants that? Who has time for that? Drugs these days are supposed to help, not hurt. While I know that it takes a while for zoloft to work, I end up feeling more morose about my situation. That's not good..esp when there drugs are being prescribed for anxious/depressed people. Come on! While this is supposed to help with my anxiety, it's making me more depressed since I am being robbed of my day and the quality of my life. Does it really take two-three weeks for these side effects to clear? I can't believe one has to go through this torture to feel better.

Posted by: Kristen at November 11, 2006 7:05 PM

I have been on zoloft for anxiety for about 4 weeks now. It really started to kick in this week and I haven't had any panic attacks and haven't felt anxious at all. The first couple of weeks I was yawning nonstop and felt a little nauseated but that has gone away. I heard a lot of people say it caused them to have insommnia and thought it might happen to me since I have had problems with that before but it actually has helped me sleep better than ever. I have also been having headaches lately, but I don't know if it's the zoloft or just allergy problems. I also have had a decreased appetite since taking zoloft. overall, I have no real complaints about it and I think it's been working great.

Posted by: Lindsay at January 27, 2007 9:09 PM

i took zoloft 200 mg from 1996 to 2003. back off or back out of it.i think its poison.

Posted by: roe robinson at February 8, 2007 5:28 PM

I have battled with depression since I was in high school. I've taken Zoloft for two extended periods in my life. Both times I've noticed the same side effects. Although I was happy I became almost numb to the important things in my life. I stopped caring about work, starting showing up late and taking days off. My boyfriend complains that I became more messy.
So which do I choose, depression or happy numbness?

Posted by: Amy at March 15, 2007 3:31 PM

Side effects,I haven't any.Unless you call an absent libido a negative one. But, the way I see it is,if I don't want it,nothing lost.
A million positive reasons why I will always take it.For the first time in my ENTIRE life I can say I am happy.I have been on it for 9 years,200mgs.a day.I now see everything in a totaly different way I never thought possible.I am now one of those goofy people walking around with a smile on my face,one of those idiots I used to see and hated.

Posted by: Glenda at December 28, 2007 8:17 AM

This is my second round on Zoloft (Sertraline). I get more anxiety than depression, but it seems that both are intertwined to some extent. I feel exhausted at times on Zoloft and yawn ALL the time. However, exhaustion and yawning don't make me feel like I'm crazy so it is worth it to me.

Posted by: Pete at July 2, 2008 3:33 PM

I just started taking Zoloft two weeks ago and felt pretty good during the first week. Felt like I was on a caffeine high, giggling all the time and was experiencing the world through a new lens. Some of the "frying" feeling was not all too enjoyable, but overall, I liked it. On into the second week, all of those feelings seemed to taper off and I really don't feel the effects after I take it. I am on 50mg now and am wondering if I should ask my doctor about increasing to 75mg? Do the cycles change over the first several weeks and maybe I can expect something different in week 3? I was just beginning to enjoy some happiness and now I am slowly beginning to feel like my same old self again and I don't want that to happen. Most likely I am being too impatient, but is raising the dose something I should think about?

Posted by: Mali at July 10, 2008 9:24 AM

I have just started taking Sertraline/zoloft and I am on my second week. I started with 25 mg for 7days and then 50mg from then on....well after i started taking 50mg i started feeling really disconnected and like i was outside of myself so my doc suggested going back down to 25mg.....I still feel like i am really anxious and like i don't want to leave my house...almost like i am paranoid and just want to be left alone....i also have barely any motivation to do anything, which i absolutely hate!! I am taking the medicine for severe panic disorder, and intruvise thoughts along with a bit of depression.....it seems like all of these are more prominent now and all i can think about is the medication....will this subside the longer i am on it or is this some kind of sign that this is not working for me?? Any comments would be grately appreciated....thanks.....sincerely jami

Posted by: jami at July 29, 2008 1:56 PM

I have been off and on Zoloft for a year and they have helped a ton. Sometimes its almost impossible to havea n orgasm. That really sucks since i feel everything else, like I really feel like i'm going to, but then it just doesnt happen. Its not always, but its frustrating when it happens. Without zoloft though, im very angry and short tempered.

Posted by: Karen at December 18, 2008 3:01 PM

I have been taking zoloft for over 10 years and my doctor even convinced me to stay on it through my pregnancy. It has been a savior for me as I used to veer between depression and anger and I now feel pretty normal. However, I'm now questioning if I need to switch out to something else as I have been experiencing some lack of effect recently. I tried to double up my dose, and oddly, started to have nonstop yawning, so I went back to my original dose. Has anyone else had any experience with an alternate SRI drug that has the low side effects of zoloft. Prozac is too effective-makes me squirrely.

Posted by: lynn at April 21, 2009 6:55 PM

It's been 6 days and I'm starting to feel better. The first few days I woke up ravenously hungry and needed to eat every couple of hours, and I was really tired...those symptoms are both decreasing now. I was in a good mood for the first time in a while, didn't experience an overabundance of anxiety after having an intense discussion with my boss (a week ago that would have had me chewing my nails and freaking out) and I'm feeling less nervous about everything. Did have a migraine yesterday, but I'm not sure if that was related to the medicine or not.

Posted by: tr at June 24, 2009 2:59 PM

yes i eas lied to i cant get off this shit

Posted by: candi at September 23, 2009 9:46 PM

Zoloft-Pfizer is the only drug that is right for me.I've been taking Zoloft-Pfizer since 1999,and have been the happiest I have been, my entire life.
I thought it was normal to hate everyone, and **********,in my life. I was the person who took great joy in killing small animals.
Only now, I can see how I wasted, the first forty years of my life. Insurance or the pharmacy has switched me over to Sertraline, or Zoloft-Tablet Roe,even Paxil,and I can honestly say that nothing works as good as the original ZOLOFT-Pfizer.

Posted by: Glenda at October 1, 2009 2:08 PM

Zoloft is amazing. at first i wasnt very open to taking medication but after some convincing from my family and psych i thought id give it a try. I am a US Marine and I became severly depressed due to anxiety attacks that began post enlistment. My Command saw fit for me to see someone and talk about what i needed to make it by. Zoloft is amazing. Ive never felt better. Plus im losing weight. :) awesome!

Posted by: Cassandra at November 5, 2009 7:07 AM

Hey, Zoloft is AWESOME.
I took it this morning for the firt time. I know it's not a placebo because:
A. I feel it wokring in my body, head buzz, body high.
B. I havnet been this social in YEARS.

I am sincerely sorry I didn't do this years ago when my life looked like it was going down the tubes.
It may not be for everyone, but I'm so happy I might cry.

Posted by: Tom at November 14, 2009 3:47 PM

i am starting zoloft today around 3 when it gets filled. i tend to have anxiety around new people or old friends i havent seen for a while. weird huh? i also am sort of pessimistic about getting ahead in life...like it will never happen. but i am skeptical about taking this because of the neg. feedback from people. there is pos. feed back but the neg outweighs it; it seems. i am supposed totake .25mg of xanax because the anxiety is supposed to get worse at first. i told him the xanax helped alot and if i could just take that sinced it helped. but he refused? what to do?

Posted by: chris at February 9, 2010 12:54 PM

I have recently been diagnosied with severe depression and have been perscribed Zoloft. I just started it last night . How soonj should I feel the effects

Posted by: Sandra at March 5, 2010 9:16 AM

If I take Zoloft at bedtime, might that do the trick to wake up in happy mode. Its a possible med throughout the day...but, when I in the morning waking up is very sad...even get weepy/cry. I quickly take thyroid med..one hr.before eating or drinking. While the hour is passing, I prepare my 3 cats breakfast they stand in line for; clean their potty boxes, talk to them and pet them as i move around getting coffee pot ready...ck the rooms out to see what job I will tackle today..think about some groceries...etc. An hour has past...and I take zoloft, (3 other meds later.) The end.
Can you give me any idea if my plan works: Zolot before Bedtime ??

Posted by: Marge at March 22, 2010 4:11 PM

I have been on Zoloft for 3 months now for GAD, PPMD and severe mood swings. It is the best thing I've ever done for myself. I was very nervous to start the medication and had several weeks of side effects. I had insomnia, night sweats, increased anxiety and dizziness. All side effects diminished in the first month. I feel calm and in control again. I'm very happy.

Posted by: Danielle at May 27, 2010 7:56 PM

I just started taking Zoloft about 3 weeks ago and I think it's working. My husband says that I no longer have angry outbursts and that I am much more calmer than usual. I have been diagnosed with depression/bipolar disorder. I believe that I might be thinking more clearly as a result of taking this medication Zoloft. I'm starting off with 50mg's. I do feel sleepy and yawn a lot throuhout the day. I have lost a few pounds and am a little more conscientious about my obsessive compulsive disorder. I use to want to shop a lot and eat or drink more than usual. I just feel a bit more conscientious about everything. A little bit numb and sedated too. That's about all for now. It's the first week of June 2010. I'll check back in a month! Good luck everyone!

Posted by: Caroline at June 10, 2010 9:36 PM

.Male 22 ,years old my panic attacks. Started first day of 9th grade I was smoking. Weed and there they c came i wouldnt stop smoking and then i would have attacks very bad ..i thought of kfc taco bell wendys all at the same time...lol.. and my heart felt like it was coming out my chest .so i stop smoking weed and I got on zoloft. 25mg feeling good but then I would get off because I thought I was better. Now I'm older and I got off zoloft because I thought everthing would be ok I was wrong went into to deep depression and panic attacks and fucked up thoughts .stay on this drug it is the best I've used but its different for others

Posted by: brandon at August 12, 2010 4:43 PM

I have been taking Zoloft for one month for anxiety, social disorders, & depression. I never realized how bad I was until now that I feel normal. The side affects for me were even better. I have decreased appetite, which is has helped me lose weight. I have always struggled with making myself drink enough water. Now, on Zoloft, I can't get enough water. I has been the best thing that has ever happend to me. I am so much more outgoing. I have good, vivid dreams. Never bad one's. After losing my little brother a few months ago, I see him in my dreams almost every night. I love Zoloft. It is my magic pill.

Posted by: cha at November 6, 2010 3:16 PM

I started taking zoloft 4 days ago and have immediatley expierenced life changing results. The main miricle the drug has given me is the ability to have a thought and let it go. As before I would have negative thoughts throughout the day that would constanly make me feel deep fear and sadness. I do believe now I have a chemical imabalance and that is why the drug is working so well. Im able to see a different more posative reality. I havent felt this stable and ok in over 6 years. I am very thankful and feel lucky that I have found something that works for me. But everyone is so different so like I read on here earlier I wouldnt encourage or distract anyone from taking this drug. Its all up to the individual and their specific situation.

Posted by: gayle at November 21, 2010 12:04 AM

Giving Zoloft to depressed people.I would advise all people with these issues to find a natural alternative to this poison.It is known to cause suicidal thoughts.I have lost a loved one and as soon as I heard what meds they were on.I knew.Beware of this rat poison.

Posted by: keith at February 12, 2011 8:23 AM

Today is February 26th 2011, I am writing this piece as a reference point for my life. At the beginning of this year I moved into my new place, its a room and bathroom plus kitchenette with its own entrance. Its located next to the state park, montana de oro, the view from my deck is breathtaking, not that it really does anything for me. My landlords have been great, they are freindly and never bother me. The reason I moved here, was because my last house was a nightmare, one of my roomates was mentally unstable and constantly making threats to me, and was very controlling about my rental privelages, and even went as far as to not allow me to have my girlfreind over because "he didn't like her." I moved here for myself and my girlfriend. A month before i moved to my current place, in december of 2010, happened to be one of the best months in our relationship. We both felt like we grew alot closer together. However after just moving into my new place, my girlfreind and I took 2ci together one of the first few nights in my new place. It was great, we had so much fun and felt even closer. Two days later, after posting a few comments on her facebook, I noticed they weren't there, like they had been removed or deleted by her. Already having been suspicious of here actions in the past, Its like my paranoia just flared up and i freaked out and texted her what a horrible girlfreind she was. She tried to explain she had no idea what i was talking about, that she didnt remove or delete any of my comments. I didnt believe her and continued in my freakout for half a day before she finally called me crying to tell me she was breaking up with me. Its only now that I realize how unstable I've been. I was acting needy, clingy, and constantly paranoid of her actions, it didnt help that she is a musician and constantly busy, and always blowing off our plans for her career, if it really was her career and not some other guy, I'll never know, and hope i dont. After our break up I tried applying for a reserve firefighter position at my local station, I got halfway through the agility test before I finally threw up from over exertion. I was very upset about failing the test. A few days later, I took a ride on my motorcycle to clear my head and calm down, I ended up colliding with a car at about 35-40 mph and wrecking my bike. I was fine except for a concussion and a stubbed toe, still dont really know how i managed to survive the crash uninjured, I can't really say I feel all that lucky about it, even if I was. I've been trying to repair my bike with the help of my Dad but it seems like everytime we fix something theres another problem with it. I still have court from a home invasion incident that occured a few years ago looming over my head, I was scheduled to show up for january 18th, then february 9th and now supposedly in april, they just keep delaying the case to a further date. I have been so depressed, I don't do anything with myself, It feels like I havent left my house in weeks. I oversleep everyday, I no longer have any motivation to go to the gym or run. I no longer have a working motorcycle and I feel like my car is on its last legs. I deliver for Domino's pizza, I am fucked if my car dies, and I do not have enough money for a new one. A week ago I had to put my cat down. It was an old cat and it had a stroke a few months prior and was having trouble walking and using its litter box, my mom also noticed a lump on its side. My mother will be leaving for a missionary trip for half a year, so she decided it was best if we just took care of the cat now. I did not want to pay 140 dollars to have a stranger take my cat and put it on a cold table while they stick a needle in its neck and throw its corpse into a pile with all the other dead cats. I drove my cat out to my Dad's property, and petted and fed my cat for a while before I shot it in the head with a .22 short. It flailed and thrashed around for a few minutes, I kept shooting it in the head but it wouldnt stop flailing. I dug a shallow grave and burried it there that day in the storm. I am writing this because today, I just drove around aimlessly for an hour, I dont know what to do with myself. I feel totally and completely empty. Ive been having so many thoughts of killing myself and others lately. The only thing i do now besides work and video games, is train with my mossberg 500 tactical combat shotgun. Dry fire exerices, live fire exercises, quick reloading, shooting while moving, and house clearing. I have no motivation to improve myself, I have no desire to meet people or talk to them. I have decided to start taking some generic zoloft i found on the internet. I've read that its not the same as brand name and that it can make things worse, I am hoping that this is only because it was people taking the brand name that switched to generic that caused the problems, not just the generic. I have come close to killing myself and others in the past and I hope I am not destined for either, it has been such a hard draining life and I dont want to have endured it for nothing. today is the fourth day i have started taking generic zoloft or sertraline 50mg daily. I guess it can take anywhere from a week to six weeks before it can start working. Heres hoping it will start working sooner than later.

Posted by: Neal at February 26, 2011 4:04 PM

I posted earlier but wanted to ad.... The first 2 weeks I have felt really energetic, like I drank 3 cups of coffee, but by the afternoon I feel wiped out and need a nap. Well, the last 2 weeks I have started my day feeling tired and wiped out. I'm hoping it's just my body (and mind) regulating itself. The good thing is my mood has stayed consistently calm and steady which is what I really need. I am less cranky with my husband and kids - 2 yrs old and 6 months old. It's very important that they don't suffer because I can't control my frustrations. So I am very happy with Zoloft so far.

Posted by: Mandy at April 8, 2011 1:57 PM

Hello all.

I've been taking generic Zoloft for about 9 months now and feel much better. I've had pretty bad social anxiety my entire life, which has somewhat been corrected with Zoloft. The problem is I have no energy or motivation. Does anyone know of any way to get some of that energy back? I think Zoloft is great and don't want to go off of it, I just need my energy back.


Posted by: Scott at August 17, 2011 3:13 PM

i have been taking half of 100mg of zoloft for 4 days now, and have been noticing tiredness, and feeling weird...anyone have these symptoms the first week of taking this? and will this medicine help if im feeling effects? and im taking this for GAD generalized anxiety disorder.

Posted by: gary hiner at November 21, 2011 6:42 PM

I have been taking 50mg of zoloft for 10 years,
I had a bad reaction to advair, very anxious. dr upped dose o zoloft to 75mg , only been taking 75mg for 5 days but I am so tired and sometimes feel like I am not here. Can just upping a dose for 5 days cause this. I want to go back to 50mg.Do I have to do this slowly.?

Posted by: ann at January 17, 2012 11:20 AM

I've been taking Zoloft (Sertraline) for 2 years now and my Doctor recently increased my dosage from 50mg to 100mg and I am pleased with the increase. I hear a lot of people describe a common side effect as sexual dysfunction and not being able to reach orgasm. I was always the minute man, and I always had to deal with premature ejaculation. Since I've been taking Zoloft, my Endurance/Stamina has greatly improved and I'm having better sexual climatic results with my partner. Zoloft fixed an embarrassing sexual problem that I had and also has helped with my depression and anxiety. I would recommend Zoloft to people that suffered as I did.

Posted by: Bobby at February 16, 2012 11:02 AM

I am the same as a few other writers, l've been taking Zoloft now for around 8 months,increase in the medication has seen my anxiety disappear.. as another poster put it, l didn't realise how bad l was until now.....now l feel myself,no fear and no stresss

Posted by: Maureen at March 1, 2012 8:26 PM

I have been taking Zoloft for 1 week only, and I already and I already feel much better. Im taking at night as it makes me sleepy !

Posted by: JEWEL at May 9, 2012 10:04 AM

So good to read some positve comments!! This is my fourth time of taking sertraline. The first three times I didn't seem to notice any side effects but I think my anxiety and depression was so bad that perhaps I wouldn't notice. What I do know is it made me feel 100% better!

This time I'm on 100mg I started at 50mg but was still feeling depressed after 2 weeks. Yes I did have the anxiety but it only lasted for a few days and also some headaches but nothing that paracetemol didn't sort out. I'm more thirsty too and felt slighty queasy but not for long and I'm on day 8.I had restless legs and early morning waking but only for the first few days. My mood has completely lifted and I'm starting to feel more normal again.

For me I just need them every now and then and I'm thankful that there is something that works for me when I need them. I believe in quality of life!!

Posted by: Natalie at May 16, 2012 7:45 AM

I started taking the generic brand of Zoloft 2 weeks ago, I have started noticing I have a loss of appetite which is difficult for me because I do work out regularly and I am need of those nutrients. I make myself eat although I am not hungry but the problem I am experiencing is after eating I am nauseous and light headed. I didn't know if anyone else had these problems and if this normal to have that reaction. I do miss eating food! Although it won't hurt me to lose a few pounds. Other than that I have noticed positive effects in my attitude...:))

Posted by: meg at June 13, 2012 1:01 PM

Today is my first day take zoloft.
Only 25mg.I felt so sad ,even worse before I took the medicine.The only thing i want to do is hide myself and cry all the time.
I just wait to see what will happen next day.

Posted by: lancy at July 18, 2012 5:28 PM

I'm 14 and have been taking 100 mg of zoloft for 9 years and my doctor wants to make it 150 is that a lot?

Posted by: emily at August 7, 2012 6:30 PM

I have struggled with anxiety and panic attacks for 15 years.I started taking zoloft eight months ago and it took it all away.i can hold a job down and start living life again.I was feeling so good I forgot to take my pill for a week and started having side affects,dizzy,weird feeling in the body.it will pass just have to remember to take my pill Iam on 50 mg everyones body are diffiernt some meds work better for some then others.no meds are good for you but its better then suffering for years when there is somthing to help you.I would rather have side affect that will go away then living with panic attacks...good luck to everyone that suffers with this disorder...

Posted by: tona at August 8, 2012 2:07 PM

I have been taking zoloft on and off over the past year.. My new doctor wants to up it to 50mg from 25, I havent taken any in the past month. what will happen if I just start taking 100mg because that what he wants me at and the 25mg did absolutely nothing!

Posted by: Shelby at October 9, 2012 5:59 PM

I have been on Zoloft for 13 years now,before i was on Zoloft i had social anxiety so bad i couldn't even leave my house not even to stand on my door step or have people in my home. It took me 2 years to get the courage to go to the doctors to get a prescription but i am glad i did because it gave me my life back and while i still have times that i have anxiety it is not where near what it used to be i can do things with my kids now and go places and enjoy my life again. I am so happy

Posted by: Shelly at November 21, 2012 9:49 PM

Been on Zoloft 3 weeks now. I feel great!!! No more negative thought, anxiety or obsessing. I have more patience in general and feel more sociable. Greatest bonus of all, was the lessen of appetite. I was an emotional binger. I ate to relieve stress. Food was my crutch. But I dont binge anymore!!!! I haven't checked the scales, but I feel lighter. I feel like an improved version of me. I can handle anything! Thanks Zoloft!!!

Posted by: Happygirl at February 10, 2013 3:16 AM

After years of very heavy depression and drifting hopelessly from one course of Fluoxetine to the next a new doctor prescribed me 50mg of Sertraline. After a turbulent three days I felt a surge of relief and my depression lifted fully for the first time in decades. three months in and with a new dosage of 125mg I feel more capable now than I have done in years and perhaps ever. Cannot recommend this medication highly enough, just praying that it's effects are lasting as I could not face going back to being the person I was with depression.

Posted by: DC at May 17, 2013 5:56 PM

I have been taking Zoloft for depression for 3 weeks, at first I started feeling better then I stopped eating properly always tightly clenched jaw as if I was on amphetamines, I have never been more sad, angry and felt so worthless since taking them, my nightmares are so vivid I often wake up, I didn't even open last packet of Zoloft I emptied every last little fucking tablet down drain, never touching Zoloft again, If you have serious depression like me this shit will make it worse

Posted by: Justin at February 1, 2014 8:40 AM

ive recently stopped taking suboxone 2mgs ,Zoloft,tramadol, and klonipin. not by choice. I have no doctor . I take care of my disabled mom and now my dog due to a car hitting him. neither of them can walk. my sisters just passed and im an addict whom was trying to overcome it. im stressed beyond stressed right now. im sooooo sick and cant take care of me much less anyone else. please someone help me im very scared.

Posted by: mia at February 1, 2014 11:05 PM

Can someone please advise, taking 50mg Zoloft for almost three weeks.for panic/anxiety. Tried taking at nite, couldn't sleep. Tried in am. Total disaster, jelly legs, feel faint and sweaty,dizzy like. What's going on with me here? It controls panic, but when should I take it and when do side affects go away? I just came off cymbalta for over ten years.anyone else have this happen? Did it pass? Seems to be better than effexor and cymbalta,side affects wise.seems nite time has less side affects but what time do you take yours?

Posted by: tiffster1 at May 15, 2014 3:27 AM

I was on Zoloft 4 years up to 200mg at the end with the added welbutrine. I have been off of it for 6 months and been put on Viibryd. I unable to orgasim for a long time. It is not getting any better. I have no problem getting an errection but can no longer climax even after 4 hours of sex, it's killing me.. Am I permentaly broken?

Posted by: Corerouter at May 27, 2014 6:58 PM

My husband has been taking Zoloft for one month now. I noticed the difference in his personality right away. He went from a grumpy, moody, sarcastic, negative person to a nice, patient, and kind person. Its amazing how a medication can correct a person chemically and it changes EVERYTHING. I am amazed and so thankful that he is taking Zoloft. I was on the verge of getting depressed myself thinking of living with him "till death due us part" with his ugly personality but now I have hope :)

Posted by: Kayzen at March 16, 2015 11:33 AM

i started taking Zoloft one year ago and I am still taking it makes me better but a always felling tiered and I don't have any incentive to work and any other activity after started taking Zoloft first I started with 50mg then i50 but now its i25mg i would appreciate your help in this matter.

Posted by: tomik at May 20, 2015 1:56 PM

I started the generic of Zoloft yesterday, so I cut 100mg in half to 50mg as directed and about 2-4 hours after taking the pill, I noticed a very positive feeling as back to normal. I saw the psychiatrist for feeling down, withdrawn, irritable, unable to concentrate, and anxious. Now I feel totally fine. I don't notice any side effects yet. Just feeling good.

Posted by: Jeremy at September 26, 2015 11:45 AM

Years and years of struggling and bad luck, feelings that I'm hated by everyone. My family torn apart after my lovely Dad died, miserable, overweight, hopeless. Got into such a dark place. I couldn't even tell my partner because I felt like a miserable wife and he would only worry.Felt like running away to Spain or something and just going missing...starnge I know.I hit my worse point when laying in bed a few weeks ago thinking whats the point, I could not cope with these bad feeling racing around my head anymore, i started to talk to my late father as if he was there in the room to the point I was begging for him to help me and cried my eyes out.I then saw my GP who put me on 100mg Setraline.A week later I was going for a walk in my lunch our, I suddenly felt happy and peaceful, I started to notice the sunshine and the nice things around me.It was a feeling of I felt better for the first time in years.I sat down closed my eyes and felt the warmth of the sun on my face.Anyone who says " its just the drugs" is a complete idiot. I was obviously suffering from some sort of imbalance in my body, and you dont realise how ill you were until, like me, you are suddenly feeling so much better. People take medication for all different things like Diebetes, heart problems, arthritis so why suffer when you have a chemical inbalance in your brain. I am so pleased I started taking Setraline for me, forget what people say if you need it, you need it! Don't be afraid of getting a little bit of help if you are suffering. With love to all of you out there who are suffering with this. xxx

Posted by: Terese Trott at February 18, 2016 6:03 PM

I have been in severe depression/ anxiety for over 10 years and have always been against taking medications. I just started using Zoloft and I can tell you I should have done this years ago. There are a couple of side effects that I noticed such as the aforementioned night sweats, dreams, occasional dizziness but nothing bad. This medication has changed my life! To anyone out there that is skeptical of this drugs efficacy; I implore you to at least try it out with a doctor's supervision.

Posted by: Rob at April 23, 2017 5:53 PM

Start a Blog

Many people who are depressed simply lack the ability to channel their energies or express themselves. Sometimes just by writing things down it is easy to feel better about things that happen to you.

If you think expressing yourself or writing your thoughts down might help you then you may want to start a blog. Wordpress is 100% free and easy to use.

Here is my friend Heather's Health Bee, which is about recovering from depression and other related illnesses.